Wang Liqiang was discriminated and abused by other children because of ankylosing spondylitis, so he shut his true feelings from others since he was a child. He takes harmonica as a friend once he came upon it. His father，Wang Qingguo, has took him to a lot of hospitals but still has no effect. Knowing that treatment won’t help, the father still wants to give the close-minded child a hope and make him out of the shadows deep inside, so he took his son embarked on the journey of conquering disease. In the strange city, Wang Liqiang met Zhou Xue, a blind girl who plays the violin because they both like music. By becoming acquainted with each other, Wang Liqiang knows that Zhou Xue also has a bizarre background. Zhou Xue infected Wang Liqiang with her optimistic and positive attitude towards life. He began to change his life, and understand the true meaning of life.